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Dosing Guide: Semaglutide & Tirzepatide Explained Clearly

Written by: Linda Moleon

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Published on

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Time to read 5 min

Comprehensive Dosing Guide for Semaglutide and Tirzepatide Medications


Semaglutide and Tirzepatide are widely prescribed injectable medications for managing type 2 diabetes and obesity. Following the correct dosing schedule is vital for ensuring optimal results while minimizing side effects. In this comprehensive dosing guide, we’ll walk you through the recommended dosing schedules for these these life-changing treatments. Understanding the correct dosing of these medications is crucial for their success.

Purpose of Medications: Semaglutide and Tirzepatide are designed to help manage type 2 diabetes and support weight loss. Correct dosing of these medications is essential for optimizing their effectiveness in both blood sugar control and weight reduction. Proper dosing is an integral part of achieving these benefits.

Importance of Proper Dosing: Following the correct dosing schedule for Semaglutide and Tirzepatide is essential. Without consistent adherence to the dosing schedule, results may vary significantly. It ensures that you achieve optimal results while minimizing the risk of side effects. Incorrect dosing could lead to suboptimal outcomes, so understanding your dosing requirements is crucial.

Starting Dose: Patients typically begin with a lower dose of Semaglutide or Tirzepatide to allow the body to adjust. Starting with a lower dosing level helps minimize initial side effects. The dosing is gradually increased to the maintenance level as the body adapts, ensuring a safe and effective transition.

Customized Approach: The dosing of both Semaglutide and Tirzepatide is adjusted based on individual needs, response to the medication, and underlying medical conditions. This individualized dosing strategy ensures treatments are as effective as possible. This tailored approach helps to maximize the benefits of the treatment, allowing for better blood sugar control and sustained weight loss.

Long-Term Success: Consistent adherence to dosing schedules enhances treatment effectiveness for diabetes management and sustained weight loss.

Semaglutide (Ozempic®) Dosing Schedule

Ozempic® is primarily prescribed for managing type 2 diabetes. The dosing schedule for Ozempic® must be followed closely to achieve desired outcomes. It’s effective in improving blood sugar control and offering secondary benefits in weight reduction.

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Semaglutide (Wegovy®) Dosing Schedule

Wegovy® is approved for chronic weight management, helping patients achieve sustainable weight loss with proper dietary and lifestyle changes.

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Tirzepatide (Mounjaro® and Zepbound®) Dosing Schedule

Tirzepatide, available as Mounjaro® for diabetes and Zepbound® for chronic weight management and Obstructive Sleep Apnea offers dual benefits in glucose control and significant weight loss.

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Maintenance Dosing and Weaning Off Protocols


  • Semaglutide (Ozempic®) : 0.5 mg to 2 mg once weekly, based on glycemic control needs. Adhering to the recommended dosing levels during maintenance is critical.

  • Semaglutide (Wegovy®) : 2.4 mg once weekly is the standard maintenance dose.

  • Tirzepatide (Mounjaro®/Zepbound®) : 5 mg to 15 mg once weekly, tailored to patient goals and tolerability.

Weaning Off Protocols

Weaning off GLP-1 medications, such as Semaglutide (Ozempic/Wegovy) or Tirzepatide (Mounjaro/Zepbound), should be done gradually to minimize potential side effects and ensure a smooth transition. Gradual reduction in dosing minimizes potential withdrawal effects. Below is a general protocol, but it’s essential to consult with your healthcare provider before making any changes to your medication regimen.

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1. Consult Your Healthcare Provider

  • Discuss your reasons for discontinuing the medication.
  • Review your current dose, treatment goals, and any underlying health conditions.
  • Develop a personalized plan to taper off safely.
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How Body Good Studio Supports Your Treatment Journey


At Body Good Studio, we’re dedicated to helping patients access effective treatments like Semaglutide and Tirzepatide . Here’s how we can assist:

  1. Personalized Consultations: Tailored treatment plans designed for your health and lifestyle goals. Our team ensures you follow the right dosing schedule to maximize benefits.

  2. Access to Trusted Medications : We partner with FDA-regulated and LegitScript-certified pharmacies to ensure safety and quality.

  3. Ongoing Care: From initial consultations to follow-ups, we provide the support you need to succeed in your health journey.

2. Gradual Dose Reduction

Weeks 1–2 : Reduce the weekly dose by 25%. For example, if you’re taking 1 mg, reduce to 0.75 mg.

Weeks 3–4 : Reduce the dose by another 25%. If you were on 0.75 mg, taper to 0.5 mg.

Weeks 5–6 : Further reduce by 25% to reach the lowest available dose (e.g., 0.25 mg).

Weeks 7+ : Discontinue completely if approved by your provider.

3. Maintain Lifestyle Changes

  • Focus on the healthy habits you’ve built while on GLP-1 medication, such as balanced nutrition, regular exercise, and mindful eating.
  • Continue tracking your progress and consider professional support to maintain your weight and blood sugar levels.

How Body Good Studio Supports Your Treatment Journey

At Body Good Studio , we’re dedicated to helping patients access effective treatments like Semaglutide and Tirzepatide. Here’s how we can assist:

  1. Personalized Consultations : Tailored treatment plans designed for your health and lifestyle goals.

  2. Access to Trusted Medications : We partner with FDA-regulated and LegitScript-certified pharmacies to ensure safety and quality.

  3. Ongoing Care : From initial consultations to follow-ups, we provide the support you need to succeed in your health journey.

Dr. Linda Moleon

The Author: Dr. Linda Moleon, MD

About the Author

Dr. Linda Moleon is a double board-certified Obesity Medicine Specialist and Anesthesiologist, as well as the founder and CEO of Body Good Studio. Passionate about empowering others, Dr. Moleon shares her expertise in weight loss while navigating her own journey toward better health. Through Body Good Studio, she strives to create a safe, supportive space where members can take charge of their weight loss on their own terms. Dr. Moleon understands the challenges firsthand and is committed to helping others achieve their goals with compassion and evidence-based care.

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Frequently Asked Questions

What is Body Good Studio (BGS)?

Body Good Studio (BGS) is a telehealth platform specializing in weight loss care using injectable GLP-1 medications like Semaglutides and Tirzepatides.

What are GLP-1 medications?

GLP-1 medications are weekly injectable treatments that help regulate blood sugar levels and support significant weight loss by reducing appetite and increasing feelings of fullness.

Who is eligible for the BGS weight loss program?

The BGS program is available to adults aged 18 and older who are not pregnant, breastfeeding, or diagnosed with type 1 diabetes.

What medications does BGS offer?

BGS offers Semaglutide and Tirzepatide medications, including compounded options, as well as brand-name options like Wegovy, Ozempic, and Mounjaro.

Are the medications covered by insurance?

Yes, insurance may cover medications like Wegovy, Ozempic, Mounjaro, or Zepbound, but approval depends on your health insurance provider. Compounded medications are self-pay only.

What are the side effects of GLP-1 medications?

Common side effects include nausea, vomiting, diarrhea, constipation, and fatigue. These are usually mild and subside as your body adjusts.

How do I sign up for the BGS program?

You can sign up by visiting the BGS website, completing a health consultation, and selecting your desired weight loss program.

What payment options does BGS accept?

BGS accepts payments via FSA, HSA, PayPal, and credit/debit cards. PayPal’s 'Buy Now, Pay Later' option is also available.

What is the difference between Semaglutide and Tirzepatide?

Tirzepatide is more effective, with a 22% body weight loss compared to 15% for Semaglutide. It also typically has fewer side effects.

Does BGS offer support after the weight loss program?

Yes, BGS offers maintenance programs that include oral medications or microdosed GLP-1 injections to help sustain weight loss.